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Inhibition of Receptor-Interacting Protein Kinase 1 with Necrostatin–1s ameliorates disease progression in elastase-induced mouse abdominal aortic aneurysm model

Abdominal aortic aneurysm (AAA) is a common aortic disease with a progressive nature. There is no approved pharmacological treatment to effectively slow aneurysm growth or prevent rupture. Necroptosis is a form of programmed necrosis that is regulated by receptor-interacting protein kinases (RIPs)....

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Wang, Qiwei, Zhou, Ting, Liu, Zhenjie, Ren, Jun, Phan, Noel, Gupta, Kartik, Stewart, Danielle M., Morgan, Stephanie, Assa, Carmel, Kent, K. Craig, Liu, Bo
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301478/
https://ncbi.nlm.nih.gov/pubmed/28186202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42159
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