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Inhibition of Receptor-Interacting Protein Kinase 1 with Necrostatin–1s ameliorates disease progression in elastase-induced mouse abdominal aortic aneurysm model
Abdominal aortic aneurysm (AAA) is a common aortic disease with a progressive nature. There is no approved pharmacological treatment to effectively slow aneurysm growth or prevent rupture. Necroptosis is a form of programmed necrosis that is regulated by receptor-interacting protein kinases (RIPs)....
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Опубликовано в: : | Sci Rep |
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Главные авторы: | , , , , , , , , , , |
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Nature Publishing Group
2017
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5301478/ https://ncbi.nlm.nih.gov/pubmed/28186202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42159 |
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