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Monocyte Chemoattractant Protein-1 (MCP-1) Regulates Macrophage Cytotoxicity in Abdominal Aortic Aneurysm

AIMS: In abdominal aortic aneurysm (AAA), macrophages are detected in the proximity of aortic smooth muscle cells (SMCs). We have previously demonstrated in a murine model of AAA that apoptotic SMCs attract monocytes and other leukocytes by producing MCP-1. Here we tested whether infiltrating macrop...

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Detalhes bibliográficos
Main Authors: Wang, Qiwei, Ren, Jun, Morgan, Stephanie, Liu, Zhenjie, Dou, Changlin, Liu, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954911/
https://ncbi.nlm.nih.gov/pubmed/24632850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092053
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