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Engineering the residual side chains of HAP phytases to improve their pepsin resistance and catalytic efficiency

Strong resistance to proteolytic attack is important for feed enzymes. Here, we selected three predicted pepsin cleavage sites, L99, L162, and E230 (numbering from the initiator M of premature proteins), in pepsin-sensitive HAP phytases YkAPPA from Yersinia kristensenii and YeAPPA from Y. enterocoli...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Niu, Canfang, Yang, Peilong, Luo, Huiying, Huang, Huoqing, Wang, Yaru, Yao, Bin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301473/
https://ncbi.nlm.nih.gov/pubmed/28186144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42133
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