Pyruvate kinase M2 and the mitochondrial ATPase Inhibitory Factor 1 provide novel biomarkers of dermatomyositis: a metabolic link to oncogenesis

BACKGROUND: Metabolic alterations play a role in the development of inflammatory myopathies (IMs). Herein, we have investigated through a multiplex assay whether proteins of energy metabolism could provide biomarkers of IMs. METHODS: A cohort of thirty-two muscle biopsies and forty plasma samples co...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Santacatterina, Fulvio, Sánchez-Aragó, María, Catalán-García, Marc, Garrabou, Glòria, de Arenas, Cristina Nuñez, Grau, Josep M., Cardellach, Francesc, Cuezva, José M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301421/
https://ncbi.nlm.nih.gov/pubmed/28183315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1136-5
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