Optimized creation of glioblastoma patient derived xenografts for use in preclinical studies

BACKGROUND: Glioblastoma multiforme (GBM) is the most common and lethal brain tumor in adults, highlighting the need for novel treatment strategies. Patient derived xenografts (PDX) represent a valuable tool to accomplish this task. METHODS: PDX were established by implanting GBM tissue subcutaneous...

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Pubblicato in:J Transl Med
Autori principali: William, Doreen, Mullins, Christina Susanne, Schneider, Björn, Orthmann, Andrea, Lamp, Nora, Krohn, Mathias, Hoffmann, Annika, Classen, Carl-Friedrich, Linnebacher, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301415/
https://ncbi.nlm.nih.gov/pubmed/28183348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1128-5
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