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Optimized creation of glioblastoma patient derived xenografts for use in preclinical studies
BACKGROUND: Glioblastoma multiforme (GBM) is the most common and lethal brain tumor in adults, highlighting the need for novel treatment strategies. Patient derived xenografts (PDX) represent a valuable tool to accomplish this task. METHODS: PDX were established by implanting GBM tissue subcutaneous...
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Опубликовано в: : | J Transl Med |
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Главные авторы: | , , , , , , , , |
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
BioMed Central
2017
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5301415/ https://ncbi.nlm.nih.gov/pubmed/28183348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1128-5 |
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