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Phase II, randomized, placebo-controlled study of dovitinib in combination with fulvestrant in postmenopausal patients with HR(+), HER2(−) breast cancer that had progressed during or after prior endocrine therapy
BACKGROUND: Overexpression of fibroblast growth factor receptor 1 (FGFR1), found in ≤8% of hormone receptor–positive (HR(+)), human epidermal growth factor receptor 2–negative (HER2(−)) breast cancer cases, is correlated with decreased overall survival and resistance to endocrine therapy (ET). Dovit...
Shranjeno v:
izdano v: | Breast Cancer Res |
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Main Authors: | , , , , , , , , , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
BioMed Central
2017
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5301372/ https://ncbi.nlm.nih.gov/pubmed/28183331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-017-0807-8 |
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