Netrin-1 Improves Functional Recovery through Autophagy Regulation by Activating the AMPK/mTOR Signaling Pathway in Rats with Spinal Cord Injury

Autophagy is an process for the degradation of cytoplasmic aggregated proteins and damaged organelles and plays an important role in the development of SCI. In this study, we investigated the therapeutic effect of Netrin-1 and its potential mechanism for autophagy regulation after SCI. A rat model o...

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Publicat a:Sci Rep
Autors principals: Bai, Liangjie, Mei, Xifan, Shen, Zhaoliang, Bi, Yunlong, Yuan, Yajiang, Guo, Zhanpeng, Wang, Hongyu, Zhao, Haosen, Zhou, Zipeng, Wang, Chen, Zhu, Kunming, Li, Gang, Lv, Gang
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301251/
https://ncbi.nlm.nih.gov/pubmed/28186165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42288
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