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miR‐15b mediates oxaliplatin‐induced chronic neuropathic pain through BACE1 down‐regulation

BACKGROUND AND PURPOSE: Although oxaliplatin is an effective anti‐cancer platinum compound, it can cause painful chronic neuropathy, and its molecular mechanisms are poorly understood. MicroRNAs (miRNAs) are small non‐coding RNAs that negatively regulate gene expression in a sequence‐specific manner...

詳細記述

保存先:
書誌詳細
出版年:Br J Pharmacol
主要な著者: Ito, Naomi, Sakai, Atsushi, Miyake, Noriko, Maruyama, Motoyo, Iwasaki, Hirotoshi, Miyake, Koichi, Okada, Takashi, Sakamoto, Atsuhiro, Suzuki, Hidenori
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301044/
https://ncbi.nlm.nih.gov/pubmed/28012171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13698
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