miR‐15b mediates oxaliplatin‐induced chronic neuropathic pain through BACE1 down‐regulation

BACKGROUND AND PURPOSE: Although oxaliplatin is an effective anti‐cancer platinum compound, it can cause painful chronic neuropathy, and its molecular mechanisms are poorly understood. MicroRNAs (miRNAs) are small non‐coding RNAs that negatively regulate gene expression in a sequence‐specific manner...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Ito, Naomi, Sakai, Atsushi, Miyake, Noriko, Maruyama, Motoyo, Iwasaki, Hirotoshi, Miyake, Koichi, Okada, Takashi, Sakamoto, Atsuhiro, Suzuki, Hidenori
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301044/
https://ncbi.nlm.nih.gov/pubmed/28012171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13698
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