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Immune Response Modulation of Conjugated Agonists with Changing Linker Length

We report immune response modulation with linked Toll-like receptor (TLR) agonists. Conjugating two agonists of synergistic TLRs induce an increase in immune activity compared to equal molarity of soluble agonists. Additionally, varying the distance between the agonists by changing the linker length...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:ACS Chem Biol
मुख्य लेखकों: Ryu, Keun Ah, Slowinska, Katarzyna, Moore, Troy, Esser-Kahn, Aaron
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5300779/
https://ncbi.nlm.nih.gov/pubmed/27749034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00895
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