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Immune Response Modulation of Conjugated Agonists with Changing Linker Length
We report immune response modulation with linked Toll-like receptor (TLR) agonists. Conjugating two agonists of synergistic TLRs induce an increase in immune activity compared to equal molarity of soluble agonists. Additionally, varying the distance between the agonists by changing the linker length...
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| Pubblicato in: | ACS Chem Biol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5300779/ https://ncbi.nlm.nih.gov/pubmed/27749034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00895 |
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