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Modulation of Innate Immune Responses via Covalently Linked TLR Agonists
[Image: see text] We present the synthesis of novel adjuvants for vaccine development using multivalent scaffolds and bioconjugation chemistry to spatially manipulate Toll-like receptor (TLR) agonists. TLRs are primary receptors for activation of the innate immune system during vaccination. Vaccines...
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| Wydane w: | ACS Cent Sci |
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| Główni autorzy: | , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Chemical Society
2015
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| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4665084/ https://ncbi.nlm.nih.gov/pubmed/26640818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.5b00274 |
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