Characterizing the Coding Region Determinant-Binding Protein (CRD-BP)-Microphthalmia-associated Transcription Factor (MITF) mRNA interaction

Coding region determinant-binding protein (CRD-BP) binds to the 3’-UTR of microphthalmia-associated transcription factor (MITF) mRNA to prevent its targeted degradation by miR-340. Here, we aim to further understand the molecular interaction between CRD-BP and MITF RNA. Using point mutation in the G...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: van Rensburg, Gerrit, Mackedenski, Sebastian, Lee, Chow H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5300761/
https://ncbi.nlm.nih.gov/pubmed/28182633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171196
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