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Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias.

Recurring chromosomal translocations involving chromosome 11, band q23, have been observed in acute lymphoid leukemias and especially in acute myeloid leukemias. We recently showed that breakpoints in four 11q23 translocations, t(4;11)(q21;q23), t(6;11)(q27;q23), t(9;11)(p22;q23), and t(11;19)(q23;p...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Ziemin-van der Poel, S, McCabe, N R, Gill, H J, Espinosa, R, Patel, Y, Harden, A, Rubinelli, P, Smith, S D, LeBeau, M M, Rowley, J D
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1991
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53005/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1720549/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.23.10735
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