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Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias.

Recurring chromosomal translocations involving chromosome 11, band q23, have been observed in acute lymphoid leukemias and especially in acute myeloid leukemias. We recently showed that breakpoints in four 11q23 translocations, t(4;11)(q21;q23), t(6;11)(q27;q23), t(9;11)(p22;q23), and t(11;19)(q23;p...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Ziemin-van der Poel, S, McCabe, N R, Gill, H J, Espinosa, R, Patel, Y, Harden, A, Rubinelli, P, Smith, S D, LeBeau, M M, Rowley, J D
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1991
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53005/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1720549/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.23.10735
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