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Established patterns of animal study design undermine translation of disease-modifying therapies for Parkinson’s disease

Translation of disease-modifying therapies in neurodegenerative disease has been disappointing. Parkinson’s disease (PD) was used to compare patterns of preclinical study design for symptomatic and potentially disease-modifying interventions. We examined the relationship of model, intervention type...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zeiss, Caroline J., Allore, Heather G., Beck, Amanda P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5300282/
https://ncbi.nlm.nih.gov/pubmed/28182759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171790
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