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Genome-wide screen for modifiers of Parkinson's disease genes in Drosophila

BACKGROUND: Mutations in parkin and PTEN-induced kinase 1 (Pink1) lead to autosomal recessive forms of Parkinson's disease (PD). parkin and Pink1 encode a ubiquitin-protein ligase and a mitochondrially localized serine/threonine kinase, respectively. Recent studies have implicated Parkin and Pi...

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Detalhes bibliográficos
Main Authors: Fernandes, Caroline, Rao, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094290/
https://ncbi.nlm.nih.gov/pubmed/21504582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-4-17
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