Genome-Wide Gene-Environment Study Identifies Glutamate Receptor Gene GRIN2A as a Parkinson's Disease Modifier Gene via Interaction with Coffee

Our aim was to identify genes that influence the inverse association of coffee with the risk of developing Parkinson's disease (PD). We used genome-wide genotype data and lifetime caffeinated-coffee-consumption data on 1,458 persons with PD and 931 without PD from the NeuroGenetics Research Con...

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Detalhes bibliográficos
Main Authors: Hamza, Taye H., Chen, Honglei, Hill-Burns, Erin M., Rhodes, Shannon L., Montimurro, Jennifer, Kay, Denise M., Tenesa, Albert, Kusel, Victoria I., Sheehan, Patricia, Eaaswarkhanth, Muthukrishnan, Yearout, Dora, Samii, Ali, Roberts, John W., Agarwal, Pinky, Bordelon, Yvette, Park, Yikyung, Wang, Liyong, Gao, Jianjun, Vance, Jeffery M., Kendler, Kenneth S., Bacanu, Silviu-Alin, Scott, William K., Ritz, Beate, Nutt, John, Factor, Stewart A., Zabetian, Cyrus P., Payami, Haydeh
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158052/
https://ncbi.nlm.nih.gov/pubmed/21876681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002237
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