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Mouse kappa light-chain recombination signal sequences mediate recombination more frequently than do those of lambda light chain.

Immunoglobulin and T-cell receptor genes are somatically rearranged by site-specific recombination. Recombination signal sequences (RSS) have been identified as the major targeting element of this process. Recent reports demonstrate that differences in RSS affect the frequency of recombination, sugg...

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Bibliographic Details
Main Authors: Ramsden, D A, Wu, G E
Format: Artigo
Language:Inglês
Published: 1991
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC53002/
https://ncbi.nlm.nih.gov/pubmed/1961738
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