Pharmacokinetics and exposure-effect relationships of capecitabine in elderly patients with breast or colorectal cancer

PURPOSE: The aims of the present study were (i) to investigate the impact of great age on pharmacokinetics of capecitabine and its metabolites and (ii) to evaluate the exposure/effect relationship of capecitabine in elderly patients. METHODS: Data collected from 20 elderly patients (75–92 years old)...

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Vydáno v:Cancer Chemother Pharmacol
Hlavní autoři: Daher-Abdi, Zeinab, Lavau-Denes, Sandrine, Prémaud, Aurélie, Urien, Saik, Sauvage, François-Ludovic, MARTIN, Jean, Leobon, Sophie, Marquet, Pierre, Tubiana-Mathieu, Nicole, Rousseau, Annick
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Verlag 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299968/
https://ncbi.nlm.nih.gov/pubmed/24801171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-014-2466-0
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