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Performance of the new mycophenolate assay based on IMPDH enzymatic activity for pharmacokinetic investigations and setup of Bayesian estimators in different populations of allograft recipients
A new MPA assay based on the enzymatic activity of recombinant IMPDH II (the pharmacological target of MPA) with excellent correlation with HPLC has recently been released for the measurement of MPA plasma levels. This study aimed to: (i) compare this new assay with LC-MS/MS for MPA pharmacokinetic...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Lippincott Williams & Wilkins
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2925205/ https://ncbi.nlm.nih.gov/pubmed/19571778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FTD.0b013e3181a8f0ae |
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