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Induction of tumor apoptosis through a circular RNA enhancing Foxo3 activity

Circular RNAs are a class of non-coding RNAs that are receiving extensive attention. Despite reports showing circular RNAs acting as microRNA sponges, the biological functions of circular RNAs remain largely unknown. We show that in patient tumor samples and in a panel of cancer cells, circ-Foxo3 wa...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Du, William W, Fang, Ling, Yang, Weining, Wu, Nan, Awan, Faryal Mehwish, Yang, Zhenguo, Yang, Burton B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299715/
https://ncbi.nlm.nih.gov/pubmed/27886165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.133
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