Dissecting the brown adipogenic regulatory network using integrative genomics

Brown adipocytes regulate energy expenditure via mitochondrial uncoupling, which makes them attractive therapeutic targets to tackle obesity. However, the regulatory mechanisms underlying brown adipogenesis are still poorly understood. To address this, we profiled the transcriptome and chromatin sta...

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Udgivet i:Sci Rep
Main Authors: Pradhan, Rachana N., Bues, Johannes J., Gardeux, Vincent, Schwalie, Petra C., Alpern, Daniel, Chen, Wanze, Russeil, Julie, Raghav, Sunil K., Deplancke, Bart
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299609/
https://ncbi.nlm.nih.gov/pubmed/28181539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42130
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