The neuroprotective effect of latanoprost acts via klotho‐mediated suppression of calpain activation after optic nerve transection

Latanoprost was first developed for use in glaucoma therapy as an ocular hypotensive agent targeting the prostaglandin F2α (FP) receptor. Subsequently, latanoprost showed a neuroprotective effect, an additional pharmacological action. However, although it is well‐known that latanoprost exerts an ocu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurochem
Prif Awduron: Yamamoto, Kotaro, Sato, Kota, Yukita, Masayoshi, Yasuda, Masayuki, Omodaka, Kazuko, Ryu, Morin, Fujita, Kosuke, Nishiguchi, Koji M., Machida, Shigeki, Nakazawa, Toru
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
ORIGINAL ARTICLES
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299490/
https://ncbi.nlm.nih.gov/pubmed/27859240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13902
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