The neuroprotective effect of hesperidin in NMDA-induced retinal injury acts by suppressing oxidative stress and excessive calpain activation

We found that hesperidin, a plant-derived bioflavonoid, may be a candidate agent for neuroprotective treatment in the retina, after screening 41 materials for anti-oxidative properties in a primary retinal cell culture under oxidative stress. We found that the intravitreal injection of hesperidin in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Maekawa, Shigeto, Sato, Kota, Fujita, Kosuke, Daigaku, Reiko, Tawarayama, Hiroshi, Murayama, Namie, Moritoh, Satoru, Yabana, Takeshi, Shiga, Yukihiro, Omodaka, Kazuko, Maruyama, Kazuichi, Nishiguchi, Koji M., Nakazawa, Toru
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537259/
https://ncbi.nlm.nih.gov/pubmed/28761134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06969-4
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