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Epigenetic Editing of Ascl1 Gene in Neural Stem Cells by Optogenetics
Enzymes involved in epigenetic processes such as methyltransferases or demethylases are becoming highly utilized for their persistent DNA or histone modifying efficacy. Herein, we have developed an optogenetic toolbox fused to the catalytic domain (CD) of DNA-methyltransferase3A (DNMT3A-CD) or Ten-E...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5299429/ https://ncbi.nlm.nih.gov/pubmed/28181538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42047 |
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