Immunosuppression with CD40 Costimulatory Blockade plus Rapamycin for Simultaneous Islet and Kidney Transplantation in Nonhuman Primates

The lack of a reliable immunosuppressive regimen that effectively suppresses both renal and islet allograft rejection without islet toxicity hampers a wider clinical application of simultaneous islet and kidney transplantation (SIK). Seven MHC mismatched SIKs were performed in diabetic cynomolgus mo...

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Veröffentlicht in:Am J Transplant
Hauptverfasser: Oura, Tetsu, Hotta, Kiyohiko, Lei, Ji, Markmann, James, Rosales, Ivy, Dehnadi, Abbas, Kawai, Kento, Ndishabandi, Dorothy, Smith, Rex-Neal, Cosimi, A. Benedict, Kawai, Tatsuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5298941/
https://ncbi.nlm.nih.gov/pubmed/27501203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13999
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