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Enzyme engineering: A synthetic biology approach for more effective library generation and automated high-throughput screening

The Golden Gate strategy entails the use of type IIS restriction enzymes, which cut outside of their recognition sequence. It enables unrestricted design of unique DNA fragments that can be readily and seamlessly recombined. Successfully employed in other synthetic biology applications, we demonstra...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Quaglia, Daniela, Ebert, Maximilian C. C. J. C., Mugford, Paul F., Pelletier, Joelle N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5298319/
https://ncbi.nlm.nih.gov/pubmed/28178357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171741
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