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Knockdown of HSPA9 induces TP53-dependent apoptosis in human hematopoietic progenitor cells

Myelodysplastic syndromes (MDS) are the most common adult myeloid blood cancers in the US. Patients have increased apoptosis in their bone marrow cells leading to low peripheral blood counts. The full complement of gene mutations that contribute to increased apoptosis in MDS remains unknown. Up to 2...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liu, Tuoen, Krysiak, Kilannin, Shirai, Cara Lunn, Kim, Sanghyun, Shao, Jin, Ndonwi, Matthew, Walter, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5298293/
https://ncbi.nlm.nih.gov/pubmed/28178280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170470
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