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Reduced Levels of Hspa9 Attenuates Stat5 Activation in Mouse B-cells

HSPA9 is located on chromosome 5q31.2 in humans, a region that is commonly deleted in patients with myeloid malignancies [del(5q)], including myelodysplastic syndromes (MDS). HSPA9 expression is reduced by 50% in patients with del(5q)-associated MDS, consistent with haploinsufficient levels. Zebrafi...

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Bibliografski detalji
Izdano u:Exp Hematol
Glavni autori: Krysiak, Kilannin, Tibbitts, Justin F., Shao, Jin, Liu, Tuoen, Ndonwi, Matthew, Walter, Matthew J.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375022/
https://ncbi.nlm.nih.gov/pubmed/25550197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2014.12.005
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