TLR signaling in human antigen‐presenting cells regulates MR1‐dependent activation of MAIT cells

Mucosal‐associated invariant T (MAIT) cells are an abundant innate‐like T lymphocyte population that are enriched in liver and mucosal tissues. They are restricted by MR1, which presents antigens derived from a metabolic precursor of riboflavin synthesis, a pathway present in many microbial species,...

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Detalles Bibliográficos
Publicado en:Eur J Immunol
Main Authors: Ussher, James E., van Wilgenburg, Bonnie, Hannaway, Rachel F., Ruustal, Kerstin, Phalora, Prabhjeet, Kurioka, Ayako, Hansen, Ted H., Willberg, Christian B., Phillips, Rodney E., Klenerman, Paul
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2016
Assuntos:
Innate Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297987/
https://ncbi.nlm.nih.gov/pubmed/27105778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545969
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