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Neuroprotective Strategy in Retinal Degeneration: Suppressing ER Stress-Induced Cell Death via Inhibition of the mTOR Signal

The retina is a specialized sensory organ, which is essential for light detection and visual formation in the human eye. Inherited retinal degenerations are a heterogeneous group of eye diseases that can eventually cause permanent vision loss. UPR (unfolded protein response) and ER (endoplasmic reti...

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Pubblicato in:Int J Mol Sci
Autori principali: Fan, Bin, Sun, Ying-Jian, Liu, Shu-Yan, Che, Lin, Li, Guang-Yu
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297831/
https://ncbi.nlm.nih.gov/pubmed/28106827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18010201
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