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Simultaneous Determination and Pharmacokinetic Study of Six Components in Rat Plasma by HPLC-MS/MS after Oral Administration of Acanthopanax sessiliflorus Fruit Extract

A specific and reliable HPLC-MS/MS method was developed and validated for the simultaneous determination of protocatechuic acid (PCA), scopolin, (−)-pinoresinol-4,4′-di-O-β-d-glucopyranoside (PDG), acanthoside D, acanthoside B and hyperin in rat plasma for the first time. The analytes were separated...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Du, Peng, Lei, Mingdao, Liu, Yu, Yang, Shilin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297680/
https://ncbi.nlm.nih.gov/pubmed/28036026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18010045
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