Mechanism of cyanide inhibition of the blood-clotting, vitamin K-dependent carboxylase.
Cyanide is a competitive inhibitor of carbon dioxide in the vitamin K-dependent glutamate carboxylase system, which plays a central role in the function of the blood clotting cascade. The mechanism of cyanide inhibition has been obscure for some time. At pH 7.2, cyanide (pKa = 9.21) will exist in so...
Zapisane w:
| Wydane w: | Proc Natl Acad Sci U S A |
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| Główni autorzy: | , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
1991
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52973/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1961725/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.23.10583 |
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