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Marrow adipocytes inhibit the differentiation of mesenchymal stem cells into osteoblasts via suppressing BMP-signaling

BACKGROUND: Reduced bone formation is associated with increased bone marrow fat in many bone-loss related diseases including aging, post-menopause, and anorexia nervosa. Several lines of evidence suggested the regulation of osteogenesis and adipogenesis of the bone marrow-derived mesenchymal (skelet...

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Detalhes bibliográficos
Publicado no:J Biomed Sci
Autor principal: Abdallah, Basem M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296965/
https://ncbi.nlm.nih.gov/pubmed/28173811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-017-0321-4
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