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Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation

Postnatal bone marrow houses mesenchymal progenitor cells that are osteoblast precursors. These cells have established therapeutic potential 1 but they are difficult to maintain and expand in vitro, presumably because little is known about the mechanisms controlling their fate decisions. To investig...

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Bibliografiske detaljer
Main Authors: Hilton, Matthew J., Tu, Xiaolin, Wu, Ximei, Bai, Shuting, Zhao, Haibo, Kobayashi, Tatsuya, Kronenberg, Henry M., Teitelbaum, Steven L., Ross, F. Patrick, Kopan, Raphael, Long, Fanxin
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740725/
https://ncbi.nlm.nih.gov/pubmed/18297083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1716
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