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MFN2 suppresses cancer progression through inhibition of mTORC2/Akt signaling
The mitochondrial GTPase mitofusin-2 (MFN2) has previously been reported to play a role in regulating cell proliferation, apoptosis and differentiation in a number of cell types. Here, we report that breast cancer patients with low MFN2 expression are associated with poor prognosis as compared to pa...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5296837/ https://ncbi.nlm.nih.gov/pubmed/28176801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41718 |
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