TNF-α Differentially Regulates Synaptic Plasticity in the Hippocampus and Spinal Cord by Microglia-Dependent Mechanisms after Peripheral Nerve Injury

Clinical studies show that chronic pain is accompanied by memory deficits and reduction in hippocampal volume. Experimental studies show that spared nerve injury (SNI) of the sciatic nerve induces long-term potentiation (LTP) at C-fiber synapses in spinal dorsal horn, but impairs LTP in the hippocam...

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Publicat a:J Neurosci
Autors principals: Liu, Yong, Zhou, Li-Jun, Wang, Jun, Li, Dai, Ren, Wen-Jie, Peng, Jiyun, Wei, Xiao, Xu, Ting, Xin, Wen-Jun, Pang, Rui-Ping, Li, Yong-Yong, Qin, Zhi-Hai, Murugan, Madhuvika, Mattson, Mark P., Wu, Long-Jun, Liu, Xian-Guo
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2017
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296781/
https://ncbi.nlm.nih.gov/pubmed/28123022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2235-16.2016
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