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CXCL12/CXCR4 axis induced miR-125b promotes invasion and confers 5-fluorouracil resistance through enhancing autophagy in colorectal cancer

The activation of CXCL12/CXCR4 axis is associated with potential progression of cancer, such as invasion, metastasis and chemoresistance. However, the underlying mechanisms of CXCL12/CXCR4 axis and cancer progression have been poorly explored. We hypothesized that miRNAs might be critical downstream...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Yu, Xinfeng, Shi, Wenna, Zhang, Yuhang, Wang, Xiaohui, Sun, Shiyue, Song, Zhiyu, Liu, Man, Zeng, Qiao, Cui, Shuxiang, Qu, Xianjun
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296742/
https://ncbi.nlm.nih.gov/pubmed/28176874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42226
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