A Novel Phosphoregulatory Switch Controls the Activity and Function of the Major Catalytic Subunit of Protein Kinase A in Aspergillus fumigatus

Invasive aspergillosis (IA), caused by the filamentous fungal pathogen Aspergillus fumigatus, is a major cause of death among immunocompromised patients. The cyclic AMP/protein kinase A (PKA) signaling pathway is essential for hyphal growth and virulence of A. fumigatus, but the mechanism of regulat...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Shwab, E. Keats, Juvvadi, Praveen R., Waitt, Greg, Soderblom, Erik J., Moseley, M. Arthur, Nicely, Nathan I., Asfaw, Yohannes G., Steinbach, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296607/
https://ncbi.nlm.nih.gov/pubmed/28174315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02319-16
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