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Regulatory gene mutation: a driving force behind group A Streptococcus strain- and serotype-specific variation

Data from multiple bacterial pathogens are consistent with regulator-encoding genes having higher mutation frequencies than the genome average. Such mutations drive both strain- and type- (e.g. serotype, haplotype) specific phenotypic heterogeneity, and may challenge public health due to the potenti...

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Détails bibliographiques
Publié dans:Mol Microbiol
Auteurs principaux: Sarkar, Poulomee, Sumby, Paul
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296365/
https://ncbi.nlm.nih.gov/pubmed/27868255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13584
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