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β Subunits Functionally Differentiate Human Kv4.3 Potassium Channel Splice Variants

The human ventricular cardiomyocyte transient outward K(+) current (I(to)) mediates the initial phase of myocyte repolarization and its disruption is implicated in Brugada Syndrome and heart failure (HF). Human cardiac I(to) is generated primarily by two Kv4.3 splice variants (Kv4.3L and Kv4.3S, div...

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Bibliografische gegevens
Gepubliceerd in:Front Physiol
Hoofdauteur: Abbott, Geoffrey W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296356/
https://ncbi.nlm.nih.gov/pubmed/28228734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00066
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