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Prostaglandin E2 inhibition of IL-27 production in murine dendritic cells: a novel mechanism which involves IRF1

IL-27, a multifunctional cytokine produced by antigen-presenting cells, antagonizes inflammation by affecting conventional dendritic cells (cDC), inducing IL-10, and promoting development of regulatory Tr1 cells. Although the mechanisms involved in IL-27 induction are well-studied, much less is know...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Hooper, Kirsten M, Yen, Jui-Hung, Kong, Weimin, Rahbari, Kate M, Kuo, Ping-Chang, Gamero, Ana M, Ganea, Doina
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296337/
https://ncbi.nlm.nih.gov/pubmed/28062696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601073
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