Differential effects of IFN-β on IL-12, IL-23, and IL-10 expression in TLR-stimulated dendritic cells

MS is an autoimmune disease characterized by immune cell infiltration in the CNS, leading to cumulative disability. IFN-β, used clinically in RR-MS reduces lesion formation and rates of relapse. Although the molecular mechanisms are not entirely elucidated, myeloid cells appear to be a major target...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Yen, Jui-Hung, Kong, Weimin, Hooper, Kirsten M., Emig, Frances, Rahbari, Kate M., Kuo, Ping-Chang, Scofield, Barbara A., Ganea, Doina
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2015
Assuntos:
Spotlight on Leading Edge Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600065/
https://ncbi.nlm.nih.gov/pubmed/26059829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3HI0914-453R
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