Dysregulation of B cell repertoire formation in myasthenia gravis patients revealed through deep sequencing

Myasthenia gravis (MG) is a prototypical B cell-mediated autoimmune disease affecting 20–50 per 100,000 people. The majority of patients fall into two clinically distinguishable types based on whether they produce autoantibodies targeting the acetylcholine receptor (AChR-MG) or muscle specific kinas...

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Veröffentlicht in:J Immunol
Hauptverfasser: Vander Heiden, Jason A., Stathopoulos, Panos, Zhou, Julian Q., Chen, Luan, Gilbert, Tamara J., Bolen, Christopher R., Barohn, Richard J., Dimachkie, Mazen M., Ciafaloni, Emma, Broering, Teresa J., Vigneault, Francois, Nowak, Richard J., Kleinstein, Steven H., O’Connor, Kevin C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296243/
https://ncbi.nlm.nih.gov/pubmed/28087666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601415
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