Dysregulation of B cell repertoire formation in myasthenia gravis patients revealed through deep sequencing

Myasthenia gravis (MG) is a prototypical B cell-mediated autoimmune disease affecting 20–50 per 100,000 people. The majority of patients fall into two clinically distinguishable types based on whether they produce autoantibodies targeting the acetylcholine receptor (AChR-MG) or muscle specific kinas...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Vander Heiden, Jason A., Stathopoulos, Panos, Zhou, Julian Q., Chen, Luan, Gilbert, Tamara J., Bolen, Christopher R., Barohn, Richard J., Dimachkie, Mazen M., Ciafaloni, Emma, Broering, Teresa J., Vigneault, Francois, Nowak, Richard J., Kleinstein, Steven H., O’Connor, Kevin C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296243/
https://ncbi.nlm.nih.gov/pubmed/28087666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601415
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