Mapping cell type-specific transcriptional enhancers using high affinity, lineage-specific Ep300 bioChIP-seq

Understanding the mechanisms that regulate cell type-specific transcriptional programs requires developing a lexicon of their genomic regulatory elements. We developed a lineage-selective method to map transcriptional enhancers, regulatory genomic regions that activate transcription, in mice. Since...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Zhou, Pingzhu, Gu, Fei, Zhang, Lina, Akerberg, Brynn N, Ma, Qing, Li, Kai, He, Aibin, Lin, Zhiqiang, Stevens, Sean M, Zhou, Bin, Pu, William T
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Developmental Biology and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5295818/
https://ncbi.nlm.nih.gov/pubmed/28121289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22039
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