Fully automated high-throughput chromatin immunoprecipitation for ChIP-seq: Identifying ChIP-quality p300 monoclonal antibodies

Chromatin immunoprecipitation coupled with DNA sequencing (ChIP-seq) is the major contemporary method for mapping in vivo protein-DNA interactions in the genome. It identifies sites of transcription factor, cofactor and RNA polymerase occupancy, as well as the distribution of histone marks. Consorti...

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Main Authors: Gasper, William C., Marinov, Georgi K., Pauli-Behn, Florencia, Scott, Max T., Newberry, Kimberly, DeSalvo, Gilberto, Ou, Susan, Myers, Richard M., Vielmetter, Jost, Wold, Barbara J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053718/
https://ncbi.nlm.nih.gov/pubmed/24919486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05152
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