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p27kip1: An all-round tumor suppressor

Our recent study has uncovered an additional mechanism by which the cell cycle inhibitor p27kip1 controls cell proliferation. Through its effect on the activity of the microtubule destabilizing protein Stathmin, p27kip1 modulates full H-Ras activation and, as a consequence, the MAPK signaling cascad...

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Détails bibliographiques
Publié dans:Mol Cell Oncol
Auteurs principaux: Belletti, Barbara, Fabris, Linda, Baldassarre, Gustavo
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5295474/
https://ncbi.nlm.nih.gov/pubmed/28203637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1141742
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