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p27kip1: An all-round tumor suppressor

Our recent study has uncovered an additional mechanism by which the cell cycle inhibitor p27kip1 controls cell proliferation. Through its effect on the activity of the microtubule destabilizing protein Stathmin, p27kip1 modulates full H-Ras activation and, as a consequence, the MAPK signaling cascad...

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Bibliografiske detaljer
Udgivet i:Mol Cell Oncol
Main Authors: Belletti, Barbara, Fabris, Linda, Baldassarre, Gustavo
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5295474/
https://ncbi.nlm.nih.gov/pubmed/28203637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1141742
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