Ni-Catalyzed Barton Decarboxylation and Giese Reactions: A Practical Take on Classic Transforms

Two named reactions of fundamental importance and paramount utility in organic synthesis have been reinvestigated, the Barton decarboxylation and Giese radical conjugate addition. N-hydroxyphthalimide (NHPI) based redox-active esters were found to be convenient starting materials for simple, thermal...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Qin, Tian, Malins, Lara R., Edwards, Jacob T., Merchant, Rohan R., Novak, Alexander J. E., Zhong, Jacob Z., Mills, Riley B., Yan, Ming, Yuan, Changxia, Eastgate, Martin D., Baran, Phil S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5295468/
https://ncbi.nlm.nih.gov/pubmed/27981703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201609662
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